Anergy in Memory CD4+ T Cells Is Induced by B Cells

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Anergy in memory CD4+ T cells is induced by B cells.

Induction of tolerance in memory T cells has profound implications in the treatment of autoimmune diseases and transplant rejection. Previously, we reported that the presentation of low densities of agonist peptide/MHC class II complexes induced anergy in memory CD4(+) T cells. In the present study, we address the specific interaction of different types of APCs with memory CD4(+) T cells. A nov...

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ژورنال

عنوان ژورنال: The Journal of Immunology

سال: 2008

ISSN: 0022-1767,1550-6606

DOI: 10.4049/jimmunol.181.5.3221